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Apetiz 160mg Tablet 10pcs
Apetiz Tablet: Used for palliative treatment of advanced breast or endometrial carcinoma (e.g., recurrent, inoperable, or metastatic). It should complement standard treatments like surgery, radiation, or chemotherapy, not replace them. No severe unexpected side effects have been reported, even at doses up to 1600 mg/day.
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✅ Description:
Relevant Products / প্রাসঙ্গিক পণ্য
✔️ Composition
Megestrol Acetate
✔️ Tablet: Megestrol Acetate
- Breast Cancer: 160 mg/day.
- Endometrial Carcinoma: 40–320 mg/day in divided doses.
- Treatment duration: Minimum 2 months to evaluate efficacy.
- Pediatric Use: Safety and efficacy are not established in children.
- Geriatric Use: Limited data to assess differences in response between older and younger patients.
✔️ Side Effects of Megestrol Acetate
Common:
- Weight gain (associated with increased appetite, not fluid retention).
Serious:
- Thromboembolic events (e.g., thrombophlebitis, pulmonary embolism).
- Glucocorticoid effects (e.g., new-onset or worsening diabetes, Cushing’s syndrome, adrenal insufficiency).
Others:
- Nausea, hyperglycemia, alopecia, hypertension, mood changes, hot flashes, lethargy, sweating, rash.
✔️ Drug Interaction
- With Medications: Drug interactions with Apetiz have not been extensively studied.
- With Food/Others: Estrogens and progestogens may cause fluid retention, especially at high doses or prolonged use. Use cautiously in patients prone to fluid retention.
✔️ Contraindications
- Hypersensitivity to Megestrol Acetate or any formulation component.
- Pregnancy or suspected pregnancy.
✔️ Pregnancy & Lactation
- Pregnancy: Category D. Progestational agents are not recommended during the first four months of pregnancy due to potential risks.
- Breastfeeding: Small amounts (~0.1%) of Megestrol are excreted in breast milk. Discontinue breastfeeding during treatment.
✔️ Precautions & Warnings
- General: Monitor patients closely when treating recurrent or metastatic cancer. Use cautiously in those with a history of thromboembolic disease.
- Diabetic Patients: May exacerbate diabetes, increasing insulin requirements.
✔️ Storage:
Store below 30°C in a cool, dry place, away from light and moisture. Keep out of reach of children.
⚠️Disclaimer:
At ePharma, we’re committed to providing accurate and accessible health information. However, all content is intended for informational purposes only and should not replace medical advice from a qualified physician. Please consult your healthcare provider for personalized guidance. We aim to support, not substitute, the doctor-patient relationship.
